ubiquitin protein造句

• It indirectly interacts with VHL, a gene that encodes for a tumor suppressor and ubiquitin protein ligase.
• The ubiquitin protein itself consists of 76 amino acids and has a molecular mass of about 8.5 kDa.
• In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs.
• The protein modifications can be either a single ubiquitin protein ( monoubiquitination ) or a chain of ubiquitin ( polyubiquitination ).
• DUBs also cleave single ubiquitin proteins that may have had their C-terminal tails accidentally bound to small cellular nucleophiles.
• The human protein Mitochondrial E3 ubiquitin protein ligase 1 is ~ 40 kDa in size and composed of 352 amino acids.
• Like mutations within the gene, these chromosomal changes prevent any functional ubiquitin protein ligase E3A from being produced in the brain.
• NDUFA4 has many protein-protein interactions, including ubiquitin proteins such as ubiquitin C and UBL4A, as well as CUL3 and PARK7.
• The ubiquitin protein itself is 76 amino acids long and was named due to its ubiquitous nature, as it has a highly evolving protein identified to date.
• It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 ( LDB1 / CLIM ), and causes proteasome-dependent degradation of LDB1.
• Ubiquitination ( or ubiquitylation ) is an enzymatic post-translational modification in which a ubiquitin protein is attached to a amino group ( ?-) of the substrate's lysine.
• "' Mitochondrial E3 ubiquitin protein ligase 1 "'( MUL1 ) is an enzyme that in humans is encoded by the " MUL1 " gene on chromosome 1.
• Altering the chain conformations exposes and conceals different parts of the ubiquitin protein, and the different linkages are recognized by proteins that are specific for the unique ubiquitin-binding domains ( UBDs ).
• The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs ( SKP1-cullin-F-box ), which function in phosphorylation-dependent ubiquitination.
• The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called F-box ), which often but not always recognize substrates in a phosphorylation-dependent manner.
• The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs ( SKP1-cullin-F-box ), which function in phosphorylation-dependent ubiquitination.
• USP20 belongs to the USP group and, like most DUBs, catalyse the breakage of an isopeptide bond between a lysine residue of the target protein and the terminal glycine residue of a ubiquitin protein.
• The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs ( Skp1-Cul1-F-box protein ), which often, but not always, recognize substrates in a phosphorylation-dependent manner.
• This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.